Toxicology & Pharmacology Conference to be held in Rome, Italy during March 23 - 24 2020.
Neurotoxicology
Get link
Facebook
X
Pinterest
Email
Other Apps
The term neurotoxicity refers to damage to the brain or peripheral nervous system caused by exposure to natural or man-made toxic substances. These toxins can alter the activity of the nervous system in ways that can disrupt or kill nerves. Nerves are essential for transmitting and processing information in the brain, as well as other areas of the nervous system. Due to their high metabolic rate, neurons are at the greatest risk of damage caused by neurotoxins. This is followed, in order of risk, by oligodendrocytes, astroocytes, microglia and capillary endothelium cells. Depending on a neurotoxin’s chemical profile, it will cause damage to certain parts or particular cellular elements of the nervous system. Non-polar substances are more soluble in lipids and can therefore access the nervous tissue more easily than polar compounds, which are less soluble in lipids. The body’s response to neurotoxins is influenced by factors such as the neurotransmitter affected, cellular membrane integrity and the presence of detoxifying mechanisms.
Toxinology is the specialized area of science that deals specifically with animal, plant, and microbial toxins. Toxinology has been defined as "the scientific discipline dealing with microbial , plant and animal venoms, poisons and toxins". "Toxinology includes more than just the chemistry and mode of action of a toxin. It deals also with the biology of venom- or poison-producing organism, the structure and function of the venom apparatus, as well as the use of the venom or poison, the ecological role of these compounds". Toxinology has also been defined as "the science of toxic substances produced by or accumulated in living organisms, their properties, and their biological significance for the organisms involved". For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact ...
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
Systems Toxicology as a branch of science that aims to quantitatively understand, model, and predict the response of cells to external stimuli and expand this to model organ and body systems. Within the context of chemical exposure measurements and a causal succession of molecular events linking exposures with toxicity and eventual disease outcome, Systems Toxicology allows us to build a detailed understanding of the mechanisms by which biological systems respond to toxicants , and to use this understanding to assess the risk of chemicals, drugs and consumer products. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
Comments
Post a Comment