Toxicology & Pharmacology Conference to be held in Rome, Italy during March 23 - 24 2020.
Drug Discovery and Toxicology Screening
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Drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity, efficacy/potency, metabolic stability, and oral bioavailability. Once a compound that fulfills all of these requirements has been identified, the process of drug development can continue, and, if successful, clinical trials. One or more of these steps may, but not necessarily, involve computer-aided drug design. A toxicology screen is a test that determines the approximate amount and type of legal or illegal drugs that taken. It may be used to screen for drug abuse, to monitor a substance abuse problem, or to evaluate drug intoxication or overdose. Toxicology screening can be done fairly quickly. The test is most often done using a urine or blood sample. In some cases, a sample of saliva or hair may be used. The results can show the presence of one specific drug or a variety of drugs at once. Further testing may be needed to determine the exact amount of a particular drug in the body and to confirm the results.
The goal of preclinical safety assessment should be to provide some assurance that patients will be protected from any unacceptable risks by defining safe and active doses. These data have been useful in providing some assurance that severe adverse effects would not be induced in patients. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
Toxicogenomics is a branch of toxicology which applies several genomic analysis techniques to determine how chemicals, both environmental and pharmaceutical agents, react on human and ecological health. It includes technologies such as genome sequence analysis, proteomics , metabolomics, and bioinformatics to detect toxic agent-induced alterations in genetic expression, protein expression, and metabolite production; moreover, effects of these alterations on phenotypic expressions at the cellular, tissue, and organism levels is also studied. Such information provides a deeper understanding of how biologic pathways respond to toxic substances. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ Submit your abstract: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
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