Toxicology & Pharmacology Conference to be held in Rome, Italy during March 23 - 24 2020.
Toxicology and Risk Assessment
Get link
Facebook
X
Pinterest
Email
Other Apps
The risk assessment is based on a chemical characterization of the test article, published information from the toxicological literature, and tolerable exposure limits, which may be adopted from published guidelines or derived on the basis of available toxicology data. The objective of a toxicological risk assessment is to evaluate the potential health risks associated with exposure to leachable impurities, contaminants, or other residues in a medical device or drug product. Based on the data from a chemical characterization, the risk assessment is to make a determination as to whether the release of chemicals during the use of a medical device or drug formulation may represent a toxicological risk that is unacceptable from a regulatory perspective. TRA is a research-based evaluation comprised of four activities: Hazard identification and data evaluation; Exposure assessment; Dose-response analysis; Risk characterization.
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are...
Aflatoxins are a family of toxins produced by certain fungi that are found on agricultural crops such as maize, peanuts, cottonseed, and tree nuts. The main fungi that produce aflatoxins are Aspergillus flavus and Aspergillus parasiticus , which are abundant in warm and humid regions of the world For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com
Comments
Post a Comment