Toxicology and Pharmacology Summit

Nanotoxicology is the study of the toxicity of nanomaterials. Because of quantum size effects and large surface area to volume ratio, nanomaterials have unique properties compared with their larger counterparts. Nanotoxicology is a branch of bionanoscience which deals with the study and application of toxicity of nanomaterials. Nanomaterials , even when made of inert elements like gold, become highly active at nanometer dimensions. Nanotoxicological studies are intended to determine whether and to what extent these properties may pose a threat to the environment and to human beings. For instance, Diesel nanoparticles have been found to damage the cardiovascular system in a mouse model. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com

Drug toxicity refers to the level of damage that a compound can cause to an organism. The toxic effects of a drug are dose-dependent and can affect an entire system as in the CNS or a specific organ such as the liver. Drug toxicity usually occurs at doses that exceed the therapeutic efficacy of a drug; however, toxic and therapeutic effects can occur simultaneously. It can be assessed at the behavioral or physiological level. Behaviorally, drug toxicity can be exhibited in a variety of ways, for example, decreases in locomotor activity, loss of motor coordination, cognitive impairment. Examples of physiological effects include lesions to tissue, neuronal death, and disrupted hormonal cycles. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme.com

The term neurotoxicity refers to damage to the brain or peripheral nervous system caused by exposure to natural or man-made toxic substances . These toxins can alter the activity of the nervous system in ways that can disrupt or kill nerves. Nerves are essential for transmitting and processing information in the brain, as well as other areas of the nervous system. Due to their high metabolic rate, neurons are at the greatest risk of damage caused by neurotoxins. This is followed, in order of risk, by oligodendrocytes, astroocytes, microglia and capillary endothelium cells. Depending on a neurotoxin’s chemical profile, it will cause damage to certain parts or particular cellular elements of the nervous system . Non-polar substances are more soluble in lipids and can therefore access the nervous tissue more easily than polar compounds, which are less soluble in lipids. The body’s response to neurotoxins is influenced by factors such as the neurotransmitter affected, cellular membrane i...

Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are...

Food safety is a area concerned with handling, preparation, and storage of food in ways that prevent food borne illness. This includes a number of measures that should be followed to avoid potentially severe health hazards. There is also evidence that organic food often contains relatively high amounts of natural toxic compounds produced by fungi or plants, whereas corresponding conventional food tends to contain more synthetic toxins such as pesticide residues, toxins and other contaminants and additives. "Food safety" implies absence or acceptable and safe levels of contaminants, adulterants, naturally occurring toxins or any other substance that may make food injurious to health on an acute or chronic basis. Food toxicology is the study of the nature, properties, effects and detection of toxic substances in food and their disease manifestation in humans. Radioactive elements, heavy metals, or the packing materials used in food processing are examples of such substances....

Toxinology is the specialized area of science that deals specifically with animal, plant, and microbial toxins. Toxinology has been defined as "the scientific discipline dealing with microbial , plant and animal venoms, poisons and toxins". "Toxinology includes more than just the chemistry and mode of action of a toxin. It deals also with the biology of venom- or poison-producing organism, the structure and function of the venom apparatus, as well as the use of the venom or poison, the ecological role of these compounds". Toxinology has also been defined as "the science of toxic substances produced by or accumulated in living organisms, their properties, and their biological significance for the organisms involved". For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact ...

Medical toxicology is a subspecialty of medicine focusing on toxicology and providing the diagnosis, management, and prevention of poisoning and other adverse effects due to medications, occupational and environmental toxicants , and biological agents . Medical toxicologists are involved in the assessment and treatment of a wide variety of problems including acute or chronic poisoning, adverse drug reactions (ADRs), drug overdoses, envenomations, substance abuse, industrial accidents, and other chemical exposures. Medical toxicology is officially recognized as a medical subspecialty. Its practitioners are physicians, whose primary specialization is generally in emergency medicine, occupational medicine, or pediatrics. For more: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/ For abstract submission: http://www.globalepisteme.org/Conference/toxicology-pharmacology-conference/submitabstract Contact us: toxicology@globalepisteme...